WEKO3
アイテム
Preparation of optically active 4-substituted,γ-lactones by lipase-catalyzed optical resolution
https://kitami-it.repo.nii.ac.jp/records/8489
https://kitami-it.repo.nii.ac.jp/records/8489b6bb2655-fa9c-4362-abdd-820d78e0d2b9
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
No3.pdf (1.0 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-11-21 | |||||
| タイトル | ||||||
| タイトル | Preparation of optically active 4-substituted,γ-lactones by lipase-catalyzed optical resolution | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | enantioselective acetylation | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | enzymatic resolution | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Grignard reaction | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | γ-lactone | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | organolithium reagent | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 著者 |
Shimotori, Yasutaka
× Shimotori, Yasutaka× Hoshi, Masayuki× Inoue, Keita× Osanai, Takeshi× Okabe, Hayato× Miyakoshi, Tetsuo |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 44800 | |||||
| 姓名 | 霜鳥, 慈岳 | |||||
| 言語 | ja | |||||
| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 44871 | |||||
| 識別子Scheme | KAKEN | |||||
| 識別子URI | https://nrid.nii.ac.jp/ja/nrid/1000000113712 | |||||
| 識別子 | 113712 | |||||
| 姓名 | 星, 雅之 | |||||
| 言語 | ja | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Optically active 4-substituted γ-lactones (3 and 4) were synthesized effectively using lipase-catalyzed optical resolution. N-methyl-4-hydroxyalkanamides (rac-1a?i) as substrates were prepared from N-methylsuccinimide. The alkylation of N-methylsuccinimide using Grignard reagents generated from various alkyl halides followed by reduction resulted in N-methyl-4-hydroxyalkanamides. The optical resolution of rac-1a?g was performed using Novozym 435-catalyzed stereoselective acetylation. The stereoselective preparation of 4-substituted γ-lactones (3 and 4) possessing various side chains such as isopentyl, phenyl, and phenethyl groups was achieved with more than 90% enantiopurity. | |||||
| 書誌情報 |
Heterocyclic communications 巻 21, 号 3, p. 165-174, 発行日 2015-06 |
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| 権利 | ||||||
| 権利情報 | c 2015 de Gruyter | |||||
| 出版者 | ||||||
| 出版者 | De Gruyter | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
