{"_buckets": {"deposit": "485ecb99-a288-4aeb-850e-25f00e23703d"}, "_deposit": {"id": "8489", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "8489"}, "status": "published"}, "_oai": {"id": "oai:kitami-it.repo.nii.ac.jp:00008489", "sets": ["1"]}, "item_3_biblio_info_186": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2015-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3", "bibliographicPageEnd": "174", "bibliographicPageStart": "165", "bibliographicVolumeNumber": "21", "bibliographic_titles": [{"bibliographic_title": "Heterocyclic communications"}]}]}, "item_3_description_184": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Optically active 4-substituted \u03b3-lactones (3 and 4) were synthesized effectively using lipase-catalyzed optical resolution. N-methyl-4-hydroxyalkanamides (rac-1a?i) as substrates were prepared from N-methylsuccinimide. The alkylation of N-methylsuccinimide using Grignard reagents generated from various alkyl halides followed by reduction resulted in N-methyl-4-hydroxyalkanamides. The optical resolution of rac-1a?g was performed using Novozym 435-catalyzed stereoselective acetylation. The stereoselective preparation of 4-substituted \u03b3-lactones (3 and 4) possessing various side chains such as isopentyl, phenyl, and phenethyl groups was achieved with more than 90% enantiopurity.", "subitem_description_type": "Abstract"}]}, "item_3_full_name_183": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "44800", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "\u971c\u9ce5, \u6148\u5cb3"}]}, {"nameIdentifiers": [{"nameIdentifier": "44871", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "1000000113712 ", "nameIdentifierScheme": "NRID", "nameIdentifierURI": "http://rns.nii.ac.jp/d/nr/1000000113712 "}], "names": [{"name": "\u661f, \u96c5\u4e4b"}]}]}, "item_3_publisher_212": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "De Gruyter"}]}, "item_3_rights_192": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "c 2015 de Gruyter"}]}, "item_3_select_195": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_3_subject_196": {"attribute_name": "\u65e5\u672c\u5341\u9032\u5206\u985e\u6cd5", "attribute_value_mlt": [{"subitem_subject": "460", "subitem_subject_scheme": "NDC"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Shimotori, Yasutaka"}], "nameIdentifiers": [{"nameIdentifier": "44794", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hoshi, Masayuki"}], "nameIdentifiers": [{"nameIdentifier": "44795", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Inoue, Keita"}], "nameIdentifiers": [{"nameIdentifier": "44796", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Osanai, Takeshi"}], "nameIdentifiers": [{"nameIdentifier": "44797", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okabe, Hayato"}], "nameIdentifiers": [{"nameIdentifier": "44798", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Miyakoshi, Tetsuo"}], "nameIdentifiers": [{"nameIdentifier": "44799", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-01-12"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "No3.pdf", "filesize": [{"value": "1.0 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1000000.0, "url": {"label": "No3.pdf", "url": "https://kitami-it.repo.nii.ac.jp/record/8489/files/No3.pdf"}, "version_id": "91510227-47b4-483e-b720-e37788125e41"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "enantioselective acetylation", "subitem_subject_scheme": "Other"}, {"subitem_subject": "enzymatic resolution", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Grignard reaction", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u03b3-lactone", "subitem_subject_scheme": "Other"}, {"subitem_subject": "organolithium reagent", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Preparation of optically active 4-substituted,\u03b3-lactones by lipase-catalyzed optical resolution", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Preparation of optically active 4-substituted,\u03b3-lactones by lipase-catalyzed optical resolution"}]}, "item_type_id": "3", "owner": "1", "path": ["1"], "permalink_uri": "https://kitami-it.repo.nii.ac.jp/records/8489", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2016-11-21"}, "publish_date": "2016-11-21", "publish_status": "0", "recid": "8489", "relation": {}, "relation_version_is_last": true, "title": ["Preparation of optically active 4-substituted,\u03b3-lactones by lipase-catalyzed optical resolution"], "weko_shared_id": 3}