| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2015-08-20 |
| タイトル |
|
|
タイトル |
Synthesis of glycosyl ferulate derivatives by amine-promoted glycosylation with regioselective hydrolysis using Novozym 435 and evaluation of their antioxidant properties |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Amine-promoted glycosylation |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Enzymatic hydrolysis |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Regioselectivity |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Antioxidant property |
| 資源タイプ |
|
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資源 |
http://purl.org/coar/resource_type/c_6501 |
|
タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 著者 |
Yasutaka, Shimotori
Kyohei, Tsutano
Kouji, Soga
Yosuke, Osawa
Masakazu, Aoyama
Tetsuo, Miyakoshi
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Various glycosyl ferulates were efficiently synthesized from 2,4,6-tetra-O-acetyl-α-d-glucopyranosyl bromide (TAGB) with amine by amine-promoted glycosylation without using heavy metal. The resulted acetylated glycosyl ferulates with acetoxyl groups at C-2, C-3 and C-4 were regioselectively deacetylated at C-4 and C-6 positions with Novozym 435. Antioxidant abilities of free ferulic acids and its synthetic glycosyl ferulates were evaluated by inhibitory effect on autoxidation of bulk methyl linoleate as well as their radical scavenging activity. The radical scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPHradical dot) decreased in the order ferulic acid > sinapinic acid ? glycosyl sinapinates ? glycosyl ferulates > p-coumaric acid > glycosyl p-coumarates. In bulk methyl linoleate, the antioxidant activity order against autoxidation was very consistent with the scavenging activity order. The results showed that glycosyl ferulates and sinapinates were effective as well as free carboxylic acid forms. |
| 書誌情報 |
en : Carbohydrate Research
巻 359,
号 1,
p. 11-17,
発行日 2012-10
|
| DOI |
|
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
http://doi.org/10.1016/j.carres.2012.06.019 |
| 出版者 |
|
|
出版者 |
Elsevier |
|
言語 |
en |
| 著者版フラグ |
|
|
言語 |
en |
|
値 |
author |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
No235.pdf (461.9 kB)
