@article{oai:kitami-it.repo.nii.ac.jp:00008876, author = {Yokawa, Ken and Kagenishi, Tomoko and Kawano, Tomonori}, issue = {7}, journal = {Bioscience, Biotechnology, and Biochemistry}, month = {}, note = {Free divalent ions of copper (Cu) are capable of generating radical species such as hydroxyl radicals in the presence of hydrogen peroxide or ascorbic acid through Harbor-Weiss-like reactions under physiological conditions. It has been reported that radical-mediated damage to DNA molecules in animal cells leads to programmed cell death. Hence it is important to seek for methods to prevent Cu-mediated DNA damage. In this study we identified on effect of Cu binding of short peptides (chiefly Gly-Gly-His tripeptide) in the prevention of DNA degradation caused by Cu-mediated reactions in the presence of hydrogen peroxide and of ascorbic acid.}, pages = {1377--1379}, title = {Prevention of Oxidative DNA Degradation by Copper-Binding Peptides}, volume = {75}, year = {2014} }