{"created":"2021-03-01T06:01:11.329907+00:00","id":8866,"links":{},"metadata":{"_buckets":{"deposit":"a0908de8-150f-4ba6-9065-84acb188cbb3"},"_deposit":{"id":"8866","owners":[],"pid":{"revision_id":0,"type":"depid","value":"8866"},"status":"published"},"_oai":{"id":"oai:kitami-it.repo.nii.ac.jp:00008866","sets":["1:87"]},"author_link":["90254","90253","90330","90256","90255","90313","90314","90315"],"item_1646810750418":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_3_biblio_info_186":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3-4","bibliographicPageEnd":"190","bibliographicPageStart":"182","bibliographicVolumeNumber":"66","bibliographic_titles":[{"bibliographic_title":"Zeitschrift fur Naturforschung C","bibliographic_titleLang":"de"}]}]},"item_3_description_184":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A previous work suggested that peptides from the histidine-containing copper-binding motifs in human prion protein (PrP) function as peroxidase-like biocatalysts catalyzing the generation of superoxide anion radicals in the presence of neurotransmitters (aromatic monoamines) and phenolics such as tyrosine and tyrosyl residues on proteins. In this study, using various phenolic substrates, the phenol-dependent superoxide-generating activities of PrP-derived peptide sequences were compared. Among the peptides tested, the GGGTH pentapeptide was shown to be the most active catalyst for phenol-dependent reactions. Based on these results, we designed a series of oligoglycyl-histidines as novel peroxidative biocatalysts, and their catalytic performances including kinetics, heat tolerance, and freezing tolerance were analysed.","subitem_description_type":"Abstract"}]},"item_3_full_name_183":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"90254","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20815633","nameIdentifierScheme":"KAKEN - 研究者検索","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/nrid/1000020815633/"}],"names":[{"name":"蔭西, 知子","nameLang":"ja"}]},{"nameIdentifiers":[{"nameIdentifier":"90253","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60750908","nameIdentifierScheme":"KAKEN - 研究者検索","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/nrid/1000060750908/"}],"names":[{"name":"陽川, 憲","nameLang":"ja"}]},{"nameIdentifiers":[{"nameIdentifier":"90330","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20335699","nameIdentifierScheme":"KAKEN - 研究者検索","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/nrid/1000020335699/"}],"names":[{"name":"河野, 智謙","nameLang":"ja"}]}]},"item_3_publisher_212":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Walter de Gruyter GmbH"}]},"item_3_relation_191":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1515/znc-2011-3-413","subitem_relation_type_select":"DOI"}}]},"item_3_rights_192":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c 1946 ? 2014: Verlag der Zeitschrift fur Naturforschung. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License."}]},"item_3_select_195":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_3_source_id_187":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1865-7125","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kagenishi, Tomoko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yokawa, Ken","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kadono, Takashi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Uezu, Kazuya","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawano, Tomonori","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-12-17"}],"displaytype":"detail","filename":"Zeitschrift fur Naturforschung C,66(3-4), P182?190.pdf","filesize":[{"value":"498.1 kB"}],"format":"application/pdf","licensetype":"license_11","url":{"label":"Zeitschrift fur Naturforschung C,66(3-4), P182?190","url":"https://kitami-it.repo.nii.ac.jp/record/8866/files/Zeitschrift fur Naturforschung C,66(3-4), P182?190.pdf"},"version_id":""}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Artifi cial Enzyme","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Peroxidase","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"PrP","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Copper-Binding Peptides from Human Prion Protein and Newly Designed Peroxidative Biocatalysts","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Copper-Binding Peptides from Human Prion Protein and Newly Designed Peroxidative Biocatalysts","subitem_title_language":"en"}]},"item_type_id":"3","owner":"1","path":["87"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-12-17"},"publish_date":"2019-12-17","publish_status":"0","recid":"8866","relation_version_is_last":true,"title":["Copper-Binding Peptides from Human Prion Protein and Newly Designed Peroxidative Biocatalysts"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2022-12-13T02:22:28.523738+00:00"}