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  1. 学術雑誌掲載済論文
  2. 洋雑誌

Copper-Binding Peptides from Human Prion Protein and Newly Designed Peroxidative Biocatalysts

https://kitami-it.repo.nii.ac.jp/records/8866
ae810205-0ef0-4976-88d2-de2274190a61
名前 / ファイル ライセンス アクション
Zeitschrift Zeitschrift fur Naturforschung C,66(3-4), P182?190 (498.1 kB)
license.icon
Item type 学術雑誌論文 / Journal Article(1)
公開日 2019-12-17
タイトル
言語 en
タイトル Copper-Binding Peptides from Human Prion Protein and Newly Designed Peroxidative Biocatalysts
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 Artifi cial Enzyme
キーワード
言語 en
主題Scheme Other
主題 Peroxidase
キーワード
言語 en
主題Scheme Other
主題 PrP
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ journal article
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
著者 Kagenishi, Tomoko

× Kagenishi, Tomoko

WEKO 90256

en Kagenishi, Tomoko

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Yokawa, Ken

× Yokawa, Ken

WEKO 90255

en Yokawa, Ken

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Kadono, Takashi

× Kadono, Takashi

WEKO 90313

en Kadono, Takashi

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Uezu, Kazuya

× Uezu, Kazuya

WEKO 90314

en Uezu, Kazuya

Search repository
Kawano, Tomonori

× Kawano, Tomonori

WEKO 90315

en Kawano, Tomonori

Search repository
著者別名
姓名
姓名 蔭西, 知子
言語 ja
著者別名
姓名
姓名 陽川, 憲
言語 ja
著者別名
姓名
姓名 河野, 智謙
言語 ja
抄録
内容記述タイプ Abstract
内容記述 A previous work suggested that peptides from the histidine-containing copper-binding motifs in human prion protein (PrP) function as peroxidase-like biocatalysts catalyzing the generation of superoxide anion radicals in the presence of neurotransmitters (aromatic monoamines) and phenolics such as tyrosine and tyrosyl residues on proteins. In this study, using various phenolic substrates, the phenol-dependent superoxide-generating activities of PrP-derived peptide sequences were compared. Among the peptides tested, the GGGTH pentapeptide was shown to be the most active catalyst for phenol-dependent reactions. Based on these results, we designed a series of oligoglycyl-histidines as novel peroxidative biocatalysts, and their catalytic performances including kinetics, heat tolerance, and freezing tolerance were analysed.
書誌情報 de : Zeitschrift fur Naturforschung C

巻 66, 号 3-4, p. 182-190, 発行日 2011
ISSN
収録物識別子タイプ ISSN
収録物識別子 1865-7125
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1515/znc-2011-3-413
権利
権利情報 c 1946 ? 2014: Verlag der Zeitschrift fur Naturforschung. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
出版者
出版者 Walter de Gruyter GmbH
著者版フラグ
値 publisher
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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