@article{oai:kitami-it.repo.nii.ac.jp:00008860, author = {Kawano, Tomonori and Kagenishi, Tomoko and Kadono, Takashi and Bouteau, Francois and Hiramatsu, Takuya and Lin, Cun and Tanaka, Kenichiro and Tanaka, Licca and Mancuso, Stefano and Uezu, Kazuya and Okobira, Tadashi and Furukawa, Hiroka and Iwase, Junichiro and Inokuchi, Reina and Balu?ka, Franti?ek and Yokawa, Ken}, issue = {6}, journal = {Communicative & Integrative Biology, Communicative & Integrative Biology}, month = {}, note = {Generation of reactive oxygen species is useful for various medical, engineering and agricultural purposes. These include clinical modulation of immunological mechanism, enhanced degradation of organic compounds released to the environments, removal of microorganisms for the hygienic purpose, and agricultural pest control; both directly acting against pathogenic microorganisms and indirectly via stimulation of plant defense mechanism represented by systemic acquired resistance and hypersensitive response. By aiming to develop a novel classes of artificial redox-active biocatalysts involved in production and/or removal of superoxide anion radicals, recent attempts for understanding and modification of natural catalytic proteins and functional DNA sequences of mammalian and plant origins are covered in this review article.}, title = {Production and removal of superoxide anion radical by artificial metalloenzymes and redox-active metals}, volume = {8}, year = {2016} }