@article{oai:kitami-it.repo.nii.ac.jp:00007728,
 author = {Konishi, Masaaki and Yoshida, Yuka and Horiuchi, Junichi},
 issue = {3},
 journal = {Journal of Bioscience and Bioengineering},
 month = {Mar},
 note = {Sophorolipids (SLs) are amphiphilic compounds produced from a variety of saccharides and vegetable oils by the yeast Starmerella bombicola and related strains, and they have commercial uses as detergents. In the present study, SL production was investigated using a corncob hydrolysate (CCH) medium derived from lignocellulosic feedstocks as a source of hydrophilic carbon substrates. Excess sulfuric acid concentrations during pretreatment of the corncobs increased the furfural concentrations and turned the CCH dark brown. The optimal sulfuric acid concentration was 1% (w/v), and the treated CCH, containing 45g/l glucose, allowed the production of 33.7g/l of SLs following 4 days of cultivation. Additional autoclaving (121°C, 20min) inhibited SL production and cell growth by 36% and 40%, respectively. Ammonium nitrate (0.1g-N/l) restored SL production to the autoclaved CCH. Finally, a cost-effective SL production of 49.2g/l, with a volumetric productivity of 12.3g/l/day, was achieved using CCH medium during batch cultivation in a jar fermentor.},
 pages = {317--322},
 title = {Efficient production of sophorolipids by Starmerella bombicola using a corncob hydrolysate medium},
 volume = {119},
 year = {2015}
}