2024-03-28T22:17:31Z
https://kitami-it.repo.nii.ac.jp/oai
oai:kitami-it.repo.nii.ac.jp:00007978
2022-12-13T02:21:28Z
1:87
Preparation of optically pure δ-lactones using diastereomeric resolution with amino acid as resolving agent
Shimotori, Yasutaka
Hoshi, Masayuki
Seki, Syota
Osanai, Takeshi
Okabe, Hayato
Ikeda, Yoshitaka
Miyakoshi, Tetsuo
δ-lactone
diastereomeric resolution
resolving agent
amino acid
Synthesis of optically pure δ-lactones by diastereomeric resolution was investigated. Amino acid derivatives, which can be obtained at a relatively low cost, were used as resolving agents. Six optically pure δ-lactones were efficiently synthesized using Cbz-L-alanine without other expensive resolving agents. Both enantiomers of δ-lactone obtained had over 98% enantiomeric excesses. This diastereomeric resolution is very efficient for the preparation of optically pure δ-lactones.
journal article
Japan Oil Chemists' Society (公益社団法人日本油化学会)
2015
application/pdf
Journal of Oleo Science
1
64
75
90
https://kitami-it.repo.nii.ac.jp/record/7978/files/2015_Preparation of optically pure δ-lactones using diastereomeric resolution with amino acid as resolving agent.pdf
eng
http://doi.org/10.5650/jos.ess14124
c 2015 by Japan Oil Chemists' Society
open access