2026-03-10T21:14:14Z https://kitami-it.repo.nii.ac.jp/oai

oai:kitami-it.repo.nii.ac.jp:02000916 2026-03-10T00:19:49Z 1:87

Random Forest Classifier of Heme Proteins Using PorphyrinDistortions and Axial Ligands of Heme Fujikawa, Hinako Kondo, Hiroko X. Kanematsu, Yusuke Takano, Yu open access This is a pre-copyedited, author-produced version of an article accepted for publication in [Chemistry Letters] following peer review. The version of record [insert complete citation information here] is available online at: [https://doi.org/10.1246/cl.230150]. Oxford Academic Random forest classifier Heme protein Heme distortion We achieved success in the construction of a random forest classifier that is capable of accurately classifying heme proteins for oxygen storage/transport function and redox function, with a high level of precision (>83%), by utilizing heme porphyrin distortions and axial ligands of heme as features. Our findings suggest that the heme distortions and the axial ligands are significantly correlated with oxidoreductase functions and oxygen storage/transport functions, respectively, all of which are commonly observed in heme proteins. Oxford Academic 2023-05-18 eng journal article AM https://kitami-it.repo.nii.ac.jp/records/2000916 https://doi.org/10.1246/cl.230150 13480715 Chemistry Letters 52 503 507 https://kitami-it.repo.nii.ac.jp/record/2000916/files/Chemistry Letters 52-503-507.pdf application/pdf 654.8 KB 2024-05-19